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What is zopiclone?

Zopiclone is a sedative-hypnotic in the “Z-drug” family. It’s prescribed in the UK, Europe, India and Australia.

What is zopiclone used for?

Short-term treatment of insomnia, meaning trouble falling asleep or staying asleep.

How does zopiclone work?

Like benzodiazepines, it boosts GABA activity, which helps the brain switch into sleep.

How should you take zopiclone?

Right before bed, and only when you can sleep for 7 to 8 hours. It is usually prescribed for no more than 2 to 4 weeks.

What are the common side effects of zopiclone?

  • Bitter or metallic taste
  • Next-day drowsiness
  • Dry mouth
  • Dizziness

What are the serious risks of zopiclone?

  • Complex sleep behaviors, such as sleepwalking or driving while not fully awake. In the U.S., eszopiclone carries an FDA boxed warning for this.
  • Dependence with long-term use
  • Rebound insomnia after stopping
  • Dangerous effects when combined with alcohol

Frequently asked questions

Is zopiclone the same as Lunesta?
They’re closely related. Eszopiclone (Lunesta) is the active half of the zopiclone molecule.

Can you take zopiclone long term?
It’s generally meant for short-term use, because tolerance and dependence can develop.

The bottom line

Zopiclone can help with short-term sleep problems. Good sleep habits and therapy for insomnia (CBT-I) are the preferred long-term solutions.


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